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Fig. 5 | Biotechnology for Biofuels

Fig. 5

From: Metabolic engineering of Escherichia coli for production of mixed isoprenoid alcohols and their derivatives

Fig. 5

Scheme of isoprenyl diphosphates flux distribution in engineered E. coli strains with and without additional overexpression of IDI. In strains NA-MBF1.1 and NA-MBF1.2 with no additional overexpression of IDI (left panel), metabolic flux of IPP is mainly directed toward formation of isoprenol through NudB. In strains NA-MBF1.1a and NA-MBF1.2a with additional overexpression of IDI (right panel), the IPP flux is diverted toward synthesis of FPP by IspA, resulting in production of farnesol as the dominant component. The circle area represents the accumulation levels of the intermediates, and the arrows represent the flux directions and the enzyme expression levels

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