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Table 4 Effect of initial glucose concentrations on cell growth and SA production of Y. lipolytica PSA3.0

From: Efficient metabolic evolution of engineered Yarrowia lipolytica for succinic acid production using a glucose-based medium in an in situ fibrous bioreactor under low-pH condition

Initial glucose (g/L) Glucose consumption (g/L) Fermentation time (h) SA titer (g/L) SA yield (g/g) SA productivity (g/L/h) DCW (g/L) Final pH
25.0 ± 2.5 25.0 ± 2.5 26.0 ± 0.5 6.9 ± 0.5 0.30 ± 0.01 0.27 ± 0.01 19.9 ± 1.5 3.9
50.0 ± 1.5 50.0 ± 1.5 29.0 ± 0.5 12.6 ± 0.3 0.26 ± 0.01 0.43 ± 0.01 33.8 ± 1.5 3.3
75.0 ± 3.1 75.0 ± 3.1 34.5 ± 1.0 18.9 ± 0.5 0.23 ± 0.01 0.55 ± 0.03 37.7 ± 2.5 3.0
100.0 ± 1.5 100.0 ± 1.5 44.5 ± 1.5 15.9 ± 0.2 0.16 ± 0.01 0.36 ± 0.02 48.1 ± 2.5 3.0
150.0 ± 2.5 129.2 ± 1.5 54.0 ± 1.5 13.9 ± 0.6 0.09 ± 0.00 0.26 ± 0.01 49.5 ± 3.0 3.0