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Table 1 Characteristics of current metabolic models of oleaginous microalgae

From: Advances in metabolic modeling of oleaginous microalgae

Organism Metabolic model (ID) Analysis Genes Reactions Metabolites Compartments Citations [references]
Chlamydomonas reinhardtii GSM 1069 143 [19]
Chlamydomonas reinhardtii GSM 1500 1200 53 [20]
Chlamydomonas reinhardtii GSM FBA 484 458 3 292 [23]
Chlamydomonas reinhardtii GSM FBA 259 10 82 [24]
Chlamydomonas reinhardtii GSM (AlgaGEM) FBA 2249 1725 1862 4 96 [25]
Chlamydomonas reinhardtii GSM (iRC1080) FBA 1080 2190 1068 10 231 [26]
Chlamydomonas reinhardtii CM FBA 280 278 47 [27]
Chlamydomonas reinhardtii GSM FBA 160 164 2 100 [28]
Chlamydomonas reinhardtii GSM FBA 280 278 0 12 [29]a
Chlamydomonas reinhardtii GSM (iBD1106) FBA 1106 2445 1959 10 10 [30]b
Chlamydomonas reinhardtii GSM (iCre1355) FBA 1355 2394 1133 10 12 [21]
Chlamydomonas reinhardtii GSM FBA/13C MFA 139 3 2 [22]
Chlorella protothecoides CM 13C MFA 24 19 0 83 [34]
Chlorella protothecoides GSM FBA/13C MFA 461 272 4 0 [31]
Chlorella pyrenoidosa CM MFA 67 0 258 [35]
Chlorella sp. CM dFBA 114 161 31 [79]
Chlorella variabilis GSM (iAJ526) FBA 526 1455 1236 5 10 [91]
Chlorella vulgaris UTEX 395 GSM (iCZ843) FBA 843 2294 1770 6 14 [32]
Chlorella vulgaris UTEX 396 GSM (iCZ946) dFBA 946 2294 1770 6 2 [33]c
Nannochloropsis gaditana GSM (iRJ1321) FBA 1321 1918 1862 4 1 [38]
Nannochloropsis salina GSM (iNS934) dFBA 934 2345 10 4 [37]
Nannochloropsis sp. GSM FBA 383 987 1024 6 0 [36]
Ostreococcus lucimarinus GSM FBA 964 1100 2 38 [49]
Ostreococcus tauri GSM FBA 871 1014 2 38 [49]
Phaeodactylum tricornutum GSM 151 88 5 289 [51]
Phaeodactylum tricornutum GSM FBA 2 12 [52]
Phaeodactylum tricornutum GSM FBA 607 849 587 6 27 [53]
Phaeodactylum tricornutum GSM (iLB1027) FBA 1027 4456 2172 6 24 [54]
Synechococcus elongatus PCC7942 GSM (iJB785) FBA 785 850 768 7 13 [78]
Synechococcus sp. PCC 7002 GSM (iSyp611) FBA 611 552 542 2 39 [92]
Synechococcus sp. PCC 7002 GSM (iSyp708) FBA 708 646 581 2 39 [93]
Synechococcus sp. PCC 7002 GSM (iSyp821) FBA 821 792 777 3 3 [94]
Synechococcus sp. PCC 7002 GSM (iSyp728) FBA 728 742 696 7 22 [95]
Synechocystis sp. PCC 6803 CM  13C MFA 29 181 [96]
Synechocystis sp. PCC 6803 CM FBA 70 46 2 165 [39]
Synechocystis sp. PCC 6803 CM FBA 43 43 [40]
Synechocystis sp. PCC 6803 GSM FBA 380 291 6 159 [41]
Synechocystis sp. PCC 6803 GSM FBA 669 882 790 2 113 [44]
Synechocystis sp. PCC 6803 GSM (iSyn811) FBA 811 956 911 2 59 [43]
Synechocystis sp. PCC 6803 GSM FBA/13C MFA 493 465 2 51 [42]
Synechocystis sp. PCC 6803 GSM (iJN678) FBA 678 863 795 3 206 [46]
Synechocystis sp. PCC 6803 GSM FBA 677 759 601 6 143 [45]
Tetraselmis sp. GSM FBA 2249 1725 1862 4 2 [47]d
Tisochrysis lutea CM EM 157 162 2 2 [50]
  1. Metabolic models are classified into two different groups: Genome-scale metabolic models (GSM) and core models (CM). The analyses were classified in: flux balance analysis (FBA), dynamic FBA (dFBA), elementary modes (EM), metabolic flux analysis (MFA), MFA using 13C tracer (13C MFA), and their combinations
  2. aModified the metabolic model of C. reinhardtii from Cogne et al. [27]
  3. bModified the metabolic model of C. reinhardtii from Chang et al. [26]
  4. cUsed the genome-scale model of C. vulgaris from Zuñiga et al. [32]
  5. dUsed the genome-scale model of C. reinhardtii from Dal’Molin et al. [25] with constraints for Tetraselmis sp.