Table 2 Differential expression of key genes related to NADPH and acetyl-CoA
Pathway | Enzyme | Gene ID | RPKM | Up/downregulated | |
|---|---|---|---|---|---|
Normal | High-oxygen | ||||
EMP | HK | SchizochytriumA2194 | 182.23 | 623.48 | 3.42 ↑ |
PFK | SchizochytriumA2542 | 181.29 | 510.14 | 2.81 ↑ | |
FBA | SchizochytriumA3279 | 912.09 | 6566.81 | 7.20 ↑ | |
PK | SchizochytriumA5008 | 360.54 | 1144.91 | 3.18 ↑ | |
SchizochytriumA0923 | 86.38 | 73.29 | 1.18 ↓ | ||
SchizochytriumA4432 | 73.81 | 53.34 | 1.38 ↓ | ||
PPP | G6PD | SchizochytriumA4008 | 219.6 | 418.4 | 1.91 ↑ |
6PGD | SchizochytriumA3341 | 553.18 | 778.82 | 1.41 ↑ | |
RPE | SchizochytriumA1080 | 81.89 | 86.24 | 1.05 ↑ | |
RPIA | SchizochytriumA0514 | 43.28 | 99.67 | 2.30 ↑ | |
TCA | CS | SchizochytriumA5632 | 483.05 | 825.88 | 1.71 ↑ |
IDH | SchizochytriumA8242 | 280.02 | 282.25 | 1.00 ↑ | |
KGDC | SchizochytriumA6065 | 7.6 | 4.7 | 1.62 ↓ | |
SchizochytriumA6274 | 387.51 | 349.09 | 1.11 ↓ | ||
SchizochytriumA8288 | 249.99 | 237.49 | 1.05 ↓ | ||
ME | SchizochytriumA9142 | 799.4 | 907.84 | 1.14 ↑ | |
ACL | SchizochytriumA2237 | 63.24 | 67.27 | 1.06 ↑ | |
Peroxisome | SOD | SchizochytriumA5508 | 123.65 | 61.05 | 2.03 ↓ |
SchizochytriumA4372 | 622.26 | 500.95 | 1.24 ↓ | ||
SchizochytriumA0375 | 1102.97 | 1083.19 | 1.02 ↓ | ||
CAT | SchizochytriumA4694 | 45.8 | 70.63 | 1.54 ↑ | |
APX | SchizochytriumA2136 | 700.57 | 395.35 | 1.77 ↓ | |