Fig. 1From: Metabolic engineering of the thermophilic filamentous fungus Myceliophthora thermophila to produce fumaric acidProduction of fumaric acid by engineered Myceliophthora thermophila. a Central metabolic pathway and key engineering strategies for production of fumaric acid. b Fumaric acid production by mutants overexpressing Spmae cultured in Erlenmeyer flask for 3 days. c Assay of Spmae copy number in mutants by RT-qPCR. CkFum; fumarase. MOC: mitochondrial malate carrier. MtSFC: succinate/fumarate mitochondrial transporter. Fr fumarate reductaseBack to article page