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Fig. 1 | Biotechnology for Biofuels

Fig. 1

From: Metabolic engineering of the thermophilic filamentous fungus Myceliophthora thermophila to produce fumaric acid

Fig. 1

Production of fumaric acid by engineered Myceliophthora thermophila. a Central metabolic pathway and key engineering strategies for production of fumaric acid. b Fumaric acid production by mutants overexpressing Spmae cultured in Erlenmeyer flask for 3 days. c Assay of Spmae copy number in mutants by RT-qPCR. CkFum; fumarase. MOC: mitochondrial malate carrier. MtSFC: succinate/fumarate mitochondrial transporter. Fr fumarate reductase

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