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TableĀ 1 Rationale design of salt bridges in LiPH8 at low pH

From: In silico-designed lignin peroxidase from Phanerochaete chrysosporium shows enhanced acid stability for depolymerization of lignin

Potential candidates for introduced salt bridges in LiPH8 Effect of mutation based on calculation of mutation energy
A16X-H101 Stabilizing effect: A16E
A36X-H39/A180X Destabilizing effect
A55X-N156X Stabilizing effect: A55R/N156E
D183-G343X Destabilizing effect
E168-A271X Destabilizing effect
Q189X-R337 Destabilizing effect
H239X-R234 Stabilizing effect: H239E
L328X-L299X Destabilizing effect