Fig. 1From: Discovery of novel geranylgeranyl reductases and characterization of their substrate promiscuityPhylogenetic tree representing the diversity of the GGR family of enzymes. The tree includes 1787 sequences of predicted GGRs from the InterPro database. Putative GGRs were selected from various organisms encompassing archaea (red), bacteria (purple), cyanobacteria (blue), alga (cyan), and plants (green). Black circles represent GGRs selected to test for isoprenoid reductase activity within this study; orange circles represent soluble proteins successfully purified and tested for reductase activity. The organismal abbreviations are listed described in Table 1Back to article page