TY - JOUR AU - Aulitto, Martina AU - Fusco, Salvatore AU - Nickel, David Benjamin AU - Bartolucci, Simonetta AU - Contursi, Patrizia AU - Franzén, Carl Johan PY - 2019 DA - 2019/02/28 TI - Seed culture pre-adaptation of Bacillus coagulans MA-13 improves lactic acid production in simultaneous saccharification and fermentation JO - Biotechnology for Biofuels SP - 45 VL - 12 IS - 1 AB - Lignocellulosic biomass is an abundant and sustainable feedstock, which represents a promising raw material for the production of lactic acid via microbial fermentation. However, toxic compounds that affect microbial growth and metabolism are released from the biomass upon thermochemical pre-treatment. So far, susceptibility of bacterial strains to biomass-derived inhibitors still represents a major barrier to lactic acid production from lignocellulose. Detoxification of the pre-treated lignocellulosic material by water washing is commonly performed to alleviate growth inhibition of the production microorganism and achieve higher production rates. SN - 1754-6834 UR - https://doi.org/10.1186/s13068-019-1382-2 DO - 10.1186/s13068-019-1382-2 ID - Aulitto2019 ER -