Fig. 1

Amino acid sequences of 10 representative ADOs. The asterisk denotes completely conserved residues, and the colon and dot denote partially conserved residues. Red squares indicate the mutation sites of the 7421ADO mutants used in the present study. The amino acid sequences of ADOs are shown in descending order of activity. The residue numbering of ADO from 9313ADO is shown at the bottom of the sequence alignments