Table 2 Substitutions of amino acid sequences from key enzymes of glycolysis (GLK1, HK) and gluconeogenesis (PEPCK) pathways
Enzyme | Gene | Substitutions | |
|---|---|---|---|
Nucleotide | Amino acid | ||
GLK1 | GLK1 | G39A T901C A1385G | M13I S301P H462R |
HK | RAG5 | C255T A1141Δ | Silence R381fs (frame-shift) |
PEPCK | PCK1 | C75T G489A T595A A921G T1101A A1156T | Silence Silence S199T Silence Silence T386S |