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Fig. 4 | Biotechnology for Biofuels

Fig. 4

From: Flow-cytometry-based physiological characterisation and transcriptome analyses reveal a mechanism for reduced cell viability in yeast engineered for increased lipid content

Fig. 4

Cellular physiological characterisation and related differentially expressed genes in strains H14, 20, 27, and 31 compared with control 24 h post-induction of gene expression: a comparison of cell growth by OD600 nm, CMI (cell-membrane integrity), intracellular ROS (reactive oxygen species), and Δψm (mitochondrial membrane potential), b number of differentially expressed genes as per gene ontology including Mito M (mitochondrial membrane, GO: 0031966), ATP (ATP metabolic process, GO: 0046034), and NADP (NADP metabolic process, GO: 0006739). c Differentially expressed genes in the ROS production-related pathways and mitochondria between H-series strains and control. The heatmaps showed the transcriptional differences in log2(fold change) (p < 0.001). *p < 0.05 (Student’s t test: two-tailed, two-sample equal variance)

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