Fig. 6

Flow diagram of incremental clustering indicating peptides shared between sequence peptide pools. Five-step incremental clustering where each red ring represents the set of peptides for a protein and the overlapping areas are peptides shared between two or more proteins. In the new iteration (indicated by the black arrow), only peptides exceeding a certain threshold of conservation are retained. Increasingly more conserved peptides were identified during five rounds of incremental clustering (illustrated as larger overlap between the rings of the Venn diagrams)