Skip to main content
Fig. 1 | Biotechnology for Biofuels

Fig. 1

From: Combining directed evolution of pathway enzymes and dynamic pathway regulation using a quorum-sensing circuit to improve the production of 4-hydroxyphenylacetic acid in Escherichia coli

Fig. 1

Biosynthetic pathway of 4-hydroxyphenylacetic acid (4HPAA). tyrA/pheA fused chorismate mutase/prephenate dehydrogenase gene, ipdC indole-3-pyruvate/phenylpyruvate decarboxylase gene from Azospirillum brasilense, ARO10 phenylpyruvate decarboxylase gene from Saccharomyces cerevisiae, tyrB tyrosine aminotransferase gene, aspC aspartate aminotransferase gene, hisC histidinol-phosphate aminotransferase gene, hpaBC 4-hydroxyphenylacetate 3-monooxygenase gene from E. coli W, aas aromatic aldehyde synthase gene from Petroselinum crispum, tydc tyrosine/DOPA decarboxylase gene from Pseudomonas putida KT2440, tynA tyramine oxidase gene, feaB phenylacetaldehyde dehydrogenase gene, yahK NADPH-dependent aldehyde reductase gene

Back to article page

Biotechnology for Biofuels and Bioproducts

ISSN: 2731-3654

Contact us