Maximum likelihood tree of the glucose oxidase–glucose dehydrogenase (GOx–GDH) cluster. Coloured circles and numbers mark the positions and counts of characterised enzymes in the tree. Right: Table of properties for the four defined clades of the tree. Listed organisms are sorted according to their appearance in the tree (top to bottom). Black coloured clades were not considered for the analysis. 1—Yang et al. ; 2—Hatzinikolaou et al. ; 3—Wohlfahrt et al. ; 4—Guo et al. ; 5—Pulci et al. ; 6—Murray et al. ; 7—Gao et al. ; 8—Piumi et al. ; 9—Mori et al. ; 10—Sygmund et al. ; 11—Sode et al.