Fig. 3

Co-expression network for predicted aplD in A. niger reveal association of this gene with vesicle-mediated transport, endosomal transport, and filamentous growth. The gene predicted to encode AplD is depicted as a grey diamond, with co-expressed genes depicted as coloured circles. Grey lines indicate co-expression co-coefficients above a Spearman cut-off of 0.7 between aplD and respective gene [38]. Benjamini–Hochberg false discovery rate corrected p values for GO-enrichment relative to the A. niger genome are depicted. Gene name nomenclature from A. niger is given. Where this is not available, names from the model fungus A. nidulans are given, or from S. cerevisiae. A single gene, An13g00740, does not have a standard name in any fungal organism. These data suggest that aplD is co-expressed with vesicle and endosomal transport proteins, and additionally with multiple genes that play crucial roles in filamentous growth