|
1
|
Overexpression of CRP variants
|
1.2% butanol
|
Global transcription factor, 308 genes with > 2.0-fold difference in expression level
|
[38, 39]
|
|
2
|
Overexpression of groESL
|
1.0% butanol
|
Folding both nascent and misfolded proteins
|
[25]
|
|
3
|
Overexpression of OmpC-TMT
|
1.5% butanol
|
Scavenging of intracellular and extracellular free radicals
|
[40]
|
|
4
|
Knockout of lon and proV
|
2.0% butanol
|
High expression of AcrAB–TolC pump
|
[19]
|
|
5
|
Overexpression of acrBI466F/M355L/S880P
|
25% increase at 0.7% butanol
|
Promoting secretion of butanol from the cell
|
[15]
|
|
6
|
Overexpression of ATF, fabD, feoA and srpABC
|
2.0% butanol
|
Synergistic effect of artificial transcription factor, fatty acid synthesis, iron-uptaking protein FeoA, efflux pump SrpABC from Pseudomonas putida
|
[41]
|
|
7
|
Overexpression of rpoD
|
2.0% butanol
|
Global transcription factor, 197 upregulated genes and 132 downregulated genes
|
[20]
|
|
8
|
Overexpression of secBT10A
|
1.8% butanol (5.3-fold improvement in T at 1.2% butanol)
|
Exporting nascent unfolded protein, improved binding affinity of substrate proteins
|
This study
|
