Drop-in biofuel production using fatty acid photodecarboxylase from Chlorella variabilis in the oleaginous yeast Yarrowia lipolytica

Table 1 Hydrocarbons produced by selected organisms, expressing different heterologous pathways

Pathway	Host	Titer	References
AAR/ACR/ADO	Rhodococcus opacus	5.2 g/L	[18]
AAR/ADO	E. coli	1.31 g/L	[34]
AAR/ADO	E. coli	~ 300 mg/L	[3]
FAP	E. coli	n.d.	[6]
CAR/ADO	S. cerevisiae	1.1 mg/L	[35]
OleT	S. cerevisiae	3.7 mg/L	[36]
UndB	S. cerevisiae	35.3 mg/L	[37]
DOX/ADO	S. cerevisiae	73.5 µg/L (304 µg/L by applying whole-cell biotransformation of pentadecanoic acid)	[38]
AAR(FAR)/ADO	Y. lipolytica	23.3 mg/L	[4]
FAP	Y. lipolytica	58.7 mg/L	This study

The enzyme abbreviations are namely AAR acyl-ACP reductase, ACR acyl-CoA reductase, ADO aldehyde-deformylating oxygenase, FAP fatty acid photodecarboxylase, OleT 450 fatty acid peroxygenase/decarboxylase, UndB desaturase-like enzyme, DOX α-dioxygenase

ISSN: 2731-3654