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Fig. 4 | Biotechnology for Biofuels

Fig. 4

From: Identification and manipulation of Neurospora crassa genes involved in sensitivity to furfural

Fig. 4

Summary of gene expression in N. crassa following exposure to furfural. Each sequence read was mapped to the Neurospora genome v12 using tophat v2.04 [67] and the expression of each gene was normalized as FPKM using cufflinks v2.02 [68] with a cutoff value of log2 ≥ 1.0 and an FDR-adjusted P value of ≤ 0.01. a Hierarchical clustering was performed on expression data from samples with cluster3.0 with blue representing low expression and yellow representing high expression. b Venn diagram of significantly differentially expressed genes in N. crassa following exposure to furfural and HMF. c All RNA-seq data sets were clustered by Euclidean distance using a variance-stabilizing transformation module in DEseq v1.14 [82]. Darker colors represent higher similarity between replicates

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