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Fig. 1 | Biotechnology for Biofuels

Fig. 1

From: Metabolic engineering of Bacillus amyloliquefaciens for enhanced production of S-adenosylmethionine by coupling of an engineered S-adenosylmethionine pathway and the tricarboxylic acid cycle

Fig. 1

Metabolic engineering strategies for coupling the engineered SAM synthesis pathway and the TCA cycle in Bacillus amyloliquefaciens. Genes are as follows: aspartokinase (encoded by lysC), bifunctional aspartokinase/homoserine dehydrogenase (thrA or metL), aspartate-semialdehyde dehydrogenase (asd), homoserine dehydrogenase (hom), homoserine O-succinyltransferase (metA), cystathionine-γ-synthase (metI, metB or YML082W), cystathionine-β-lyase (metC), cystathionine-β-synthase (mccA), methionine synthase (metE), SAM synthetase (metK or SAM2), succinyl-CoA synthetase (sucCD)

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