Table 3 Comparison of different strategies used for oil production by oleaginous yeasts using glucose as a C-source

Rhodosporidium toruloides DSMZ 4444

Batch fermentation—N limiting; pO₂ controlled (with 50% air saturation)

0.15

0.15

[39]

Saccharomyces cerevisiae ^E

Systematic engineering in S. cerevisiae for enhanced free fatty acids production; fed-batch addition of glucose to a minimal media

0.104^a

0.23^a

[40]

Y. lipolytica W29 (ATCC20460)^E

Metabolic flux pulling and in situ addition of 15% (v/v) dodecane at shake flask scale

0.14^a

0.20

[15]

Rhodosporidium toruloides DSMZ 4444^A

Cultivation in NaCl-enriched glucose-based media for yeast adaptation

0.075^a

0.21

[41]

Rhodosporidium toruloides ^A

Shake flask culturing for 96 h; Strain adapted by successive cultivations in increasing concentrations of SCBH

0.106 ± 0.005

0.20

[42]

Rhodosporidium toruloides A29

Fed-batch glucose addition to an optimized media to maintain C/N

0.26^a

0.147^a

[43]

Yarrowia lipolytica NCIM 3590

Two-stage fermentation with 5% glucose as sole carbon and nutrient source

0.066^a

0.15 ± 0.02

[17]

Yarrowia lipolytica Y-4311^E

Batch cultivation in shaking tubes with 7.5% (v/v) dodecane

0.019^a

0.25^a

[29]

Lipomyces starkeyi NBRC10381

10% Glucose in nitrogen-limited mineral medium with high inoculum size

0.28^a

0.20^a

[44]

Trichosporon. oleaginosus ATCC 20509

Fermentation with Excess O₂ in a media with C/N 75.3

0.14 ± 0.03

0.21

[45]

Yarrowia lipolytica ADgm-hi^E

Engineered cytosolic redox metabolism; Cultured in a high density fed-batch fermentation

1.3

0.269

[46]

Cryptococcus curvatus MUCL 29819

Pre-culture followed by batch fermentation with 4% glucose as a sole carbon/nutrient source

0.024^a

0.088

[13]

Cutaneotrichosporon oleaginosus (ATCC 20509)

Sole glucose batch fermentation; in situ enzymatic cell wall hydrolysis for intracellular oil recovery

0.09

nd

[47]

Lipomyces starkeyi Ls-D35 strain

Lipid production under low C/N ratio (17.9) by high cell density cultivation

nd

0.13

[48]

Yarrowia lipolytica E26E1

Batch fermentation with 16% glucose in minimal medium followed by Switchable solvent extraction (DMCHA, EB, DP) from wet cells

0.099^a

0.1^a

[37]

Yarrowia lipolytica NCIM 3590

Two-stage microbial oil production with in situ oil capturing agents (OCA); Batch fermentation 72 h; 5% glucose

0.166

0.33

Present study

Yarrowia lipolytica NCIM 3590

Oil production with continuous on-line oil capture for 378 h; Fed-batch (5% glucose) addition and OCA regeneration for 5 cycles of 72 h each

0.041

0.33

Present study