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Table 4 Itaconic acid production of acl12 overexpressing CitB#99 transformants

From: Metabolic engineering with ATP-citrate lyase and nitrogen source supplementation improves itaconic acid production in Aspergillus niger

Strain

Max. titer (g/L)

Max. productivity (g/L/h)

Yield (g/g glucose)

CitB#99

15.6

0.13

0.23

CitB #99 ACL A12 G

2.2

0.02

0.04

CitB #99 ACL F11 Z

10.5

0.11

0.15

CitB #99 ACL D12 G

14.2

0.14

0.22

CitB #99 ACL A4 R

15.2

0.14

0.23

CitB #99 ACL D10 G

15.3

0.14

0.23

CitB #99 ACL H4 Z

15.7

0.15

0.24

CitB #99 ACL G11 Z

16.2

0.15

0.24

CitB #99 ACL G8 Z

16.30

0.16

0.25

CitB #99 ACL C3 R

16.6

0.16

0.22

CitB #99 ACL A9 G

17.9

0.18

0.25

CitB #99 ACL B11 G

18.0

0.17

0.26

CitB #99 ACL E11 Z

18.4

0.17

0.26

CitB #99 ACL D9 R

18.4

0.17

0.28

CitB #99 ACL G1 Z

20.6

0.20

0.30

  1. Results are from a single representative shake flask experiment for each transformant