Fig. 4
Transcriptional response of nitrogen metabolism of C. zofingiensis to ND. Blue, black and red arrows designate down-, non- and up-regulated enzymatic steps. For proteins encoded by multiple copies of genes, the changes in total transcripts of the isogenes were employed for determining the overall regulation pattern. Heat map showing log2(fold change) values of transcripts relative to 0 h of ND. Significant difference (absolute log2(fold change) value > 1 and FDR adjusted p < 0.05; n = 3) is indicated with an asterisk. Time refers to the duration of ND. AAH allantoin amidohydrolase, AMI formamidase, AMT ammonium transporter, AMX amine oxidase, ATDI allantoate deiminase, BUP β-ureidopropionase, DHDH dihydrouracil dehydrogenase, DHP dihydropyrimidinase, DUR1 urea carboxylase, DUR2 allophanate hydrolase, DUR3 urea active transporter, GDA guanine deaminase, GDH glutamate dehydrogenase, Glu glutamate, Gln glutamine, GOGAT glutamate synthase, GS glutamine synthetase, NAR1 nitrate transporter, NAR1 family; NAR2 nitrate transporter, NAR2 family, NIR nitrite reductase, NRD nitrate reductase, NRT1 nitrate transporter, NRT1 family, NRT2 nitrate transporter, NRT2 family, 2OG 2-oxoglutarate, RPH ammonium transporter, Rh family, UAH ureidoglycolate amidohydrolase, UIAH ureidoglycine aminohydrolase, UOX urate oxidase, XDH xanthine dehydrogenase. See Additional file 3: Data S2 for the details of gene transcripts