TY - JOUR AU - He, Pinjing AU - Duan, Haowen AU - Han, Wenhao AU - Liu, Yang AU - Shao, Liming AU - Lü, Fan PY - 2019 DA - 2019/12/16 TI - Responses of Methanosarcina barkeri to acetate stress JO - Biotechnology for Biofuels SP - 289 VL - 12 IS - 1 AB - Anaerobic digestion of easily degradable biowaste can lead to the accumulation of volatile fatty acids, which will cause environmental stress to the sensitive methanogens consequently. The metabolic characteristics of methanogens under acetate stress can affect the overall performance of mixed consortia. Nevertheless, there exist huge gaps in understanding the responses of the dominant methanogens to the stress, e.g., Methanosarcinaceae. Such methanogens are resistant to environmental deterioration and able to utilize multiple carbon sources. In this study, transcriptomic and proteomic analyses were conducted to explore the responses of Methanosarcina barkeri strain MS at different acetate concentrations of 10, 25, and 50 mM. SN - 1754-6834 UR - https://doi.org/10.1186/s13068-019-1630-5 DO - 10.1186/s13068-019-1630-5 ID - He2019 ER -