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Table 4 Comparison of different fermentation processes for butanol production

From: Pathway dissection, regulation, engineering and application: lessons learned from biobutanol production by solventogenic clostridia

Fermentation process Strain Substrates Yield (g/g) Productivity (g/L/h) Titer of ABE (g/L) Refs.
Batch fermentation C. beijerinckii P260 Barley straw 0.43 0.39 26.46 [239]
C. beijerinckii BA101 Corn fibers 0.36–0.39 0.10 9.3 [33]
Fed-batch fermentation C. beijerinckii P260 Wheat straw 0.36 16.59 [240]
C. saccharoperbutylacetonicum N1–4 Synthetic medium with butyric acid 0.49 0.42 16.0 [241]
Continuous fermentation
 (i) Free cell continuous fermentation C. saccharobutylicum DSM 13864 Sago starch 0.29 0.85 9.1 [242]
C. beijerinckii BA101 Degermed corn 0.29–0.30 14.28 [194]
 (ii) Immobilized cells continuous fermentation C. acetobutylicum ATCC 55025 Corn 0.42 4.6 12.5 [243]
C. beijerinckii BA101 Synthetic medium 0.36 12.43 8.8 [244]
 (iii) Cell recycling and bleeding C. saccharoperbutylacetonicum N14 Synthetic medium 11.0 8.58 [245]
C. acetobutylicum BKM19 Clostridial growth medium (CGM) 0.34 21.1 23.5 [195]
In situ product recovery
 (i) Adsorption process
  Fed-batch fermentation C. acetobutylicum ATCC 824 Glucose 0.22 0.45  54.6  [246]
 (ii) Pervaporation process
  Batch fermentation C. acetobutylicum ATCC 824 Glucose 0.38 0.76  201.8  [247]
 (iii) Gas stripping process
  Batch fermentation C. acetobutylicum JB200 Cassava bagasse hydrolysate 0.23 0.32 108.5 [248]
  Batch fermentation C. beijerinckii BA101 Glucose 0.47 0.61 75.9 [249]
  Fed-batch fermentation C. beijerinckii BA101 Glucose 0.47 1.16 233 [138]