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Fig. 6 | Biotechnology for Biofuels

Fig. 6

From: Metabolic and evolutionary responses of Clostridium thermocellum to genetic interventions aimed at improving ethanol production

Fig. 6

Convergent mutations. Strains are sorted according to the fermentation profiles from Fig. 5 to show genes whose mutations cluster predominantly with a particular phenotype. For example, mutations in the adhE gene seem to be associated with fermentation phenotype 3. Strain LL1111 is not shown in Fig. 5. It produces mainly lactate and is thus given its own fermentation phenotype column. For each mutation, the fraction of reads supporting that mutation is given in the shaded cells. This figure only shows origin mutations, so inherited mutations are not shown. Furthermore, genes are only shown that have more than one origin mutation. A complete list of mutations in each strain is provided in Additional file 2: Table S2. aSNV = single nucleotide variation. bfs = frameshift

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