Metabolic and evolutionary responses of Clostridium thermocellum to genetic interventions aimed at improving ethanol production

Table 1 Mutations associated with changes in gene expression

Annotation name	Locus description	Parent	Strain	Fold-change	p-value
89 bp upstream of Clo1313_0099	Thiamine pyrophosphate TPP-binding domain-containing protein	LL1036	LL1042	4.33	0.0017
10 bp upstream of Clo1313_0779	Copper amine oxidase-like domain-containing protein	LL1044	LL374	0.47	0.0003
81 bp upstream of Clo1313_1055	Major facilitator superfamily MFS_1	LL1044	LL375	2.29	0.0020
8 bp upstream of Clo1313_1397	Copper amine oxidase-like domain-containing protein	LL1044	LL374	0.47	0.0010
14 bp upstream of Clo1313_1989	VTC domain	LL345	LL376	0.52	0.0001
197 bp upstream of Clo1313_2323	ABC transporter related	LL1044	LL374	2.52	0.0005

ISSN: 2731-3654