Constraints and advances in high-solids enzymatic hydrolysis of lignocellulosic biomass: a critical review

da Silva, Ayla Sant’Ana; Espinheira, Roberta Pereira; Teixeira, Ricardo Sposina Sobral; de Souza, Marcella Fernandes; Ferreira-Leitão, Viridiana; Bon, Elba P. S.

doi:10.1186/s13068-020-01697-w

Biotechnology for Biofuels and Bioproducts

Table 3 Published patents recovered in the database of the World Intellectual Property Organization (WIPO) related to high-solids enzymatic hydrolysis

From: Constraints and advances in high-solids enzymatic hydrolysis of lignocellulosic biomass: a critical review

Patent title	Applicant/current assigned	Date of publication or grant^a	Summary of the invention	References
Reactor for continuous saccharification of high-solids biomass	SK Innovation Co., LTD	2015	Design of a reactor for continuous saccharification of biomass at high-solids loading	[172]
High-solids biomass slurry generation for enhanced efficiency hydrolysis processing and equipment design to yield the same	Edeniq, INC.	2017	Shear cutting elements as impellers and a “pump ring” to enable high-solids enzymatic hydrolysis with high yields	[173]
Continuous countercurrent enzymatic hydrolysis of pretreated biomass at high-solids concentrations	Granbio Intellectual Property Holdings LLC	2018	Method of continuous countercurrent enzymatic hydrolysis in a reactor with perforated screw blades	[174]
Non-pressurized pretreatment, enzymatic hydrolysis and fermentation of waste fraction	Renescience AS	2018	High-solids enzymatic hydrolysis conducted in a free-fall mixing reactor	[175]
Enzymatic hydrolysis of cellulose	Borregaard AS	2012	Use of three hydrolysis tanks to conduct high-solids enzymatic hydrolysis	[176]
Process for improving the hydrolysis of cellulose in high-consistency systems using one or more unmixed and mixed hydrolysis reactors	Iogen Energy Corporation	2014	The use of an initial unmixed reactor and subsequently a mixed reactor	[177]
Enzymatic hydrolysis of biomasses having a high dry matter (DM) content	Inbicon A/S	2010	Design of a horizontal reactor for saccharification of biomass at high-solids loading	[178]
High-consistency enzymatic hydrolysis for the production of ethanol	Phillips Richard	2012	Thickening process by recycling the filtrate	[179]
Methods and systems for enzymatic hydrolysis of pretreated biomass at high-solids concentrations	Granbio Intellectual Property Holdings LLC	2019	Use of a surfactant and substrate recycling during high-solids enzymatic hydrolysis	[180]
Method for the hydrolysis of lignocellulosic biomass	Fiberight Limited	2018^b	Use of a surfactant during high-solids enzymatic hydrolysis	[181]
Process for simultaneous saccharification and fermentation for production of ethanol	E. I. DuPont de Nemours and Company	2011	Simultaneous saccharification and fermentation at high-solids loading	[182]
High-solids enzymatic hydrolysis and fermentation of pretreated biomass	Abengoa Bioenergy New Technologies, LLC	2017	Temperature and dewatering control for high-solids enzymatic hydrolysis	[183]
Production of fermentable biomass sugars using high-solids enzymatic hydrolysis	API Intellectual Property Holdings, LLC	2015	Liquefaction and separation of solid and liquid streams to different uses	[184]
Enzymatic hydrolysis of pre-treated biomass	Andritz INC	2012	Whole method to conduct high-solids enzymatic hydrolysis	[185]
Methods of enabling enzymatic hydrolysis and fermentation of lignocellulosic biomass with pretreated feedstock following high-solids storage in the presence of enzymes	Catchlight Energy LLC	2012	The use of enzymes during storage and/or transportation of biomass at high-solids loading	[186]
Process for the rapid hydrolysis of high-solids biomass	Beta Renewables S.p.A.	2015	Continuous process of high-solids enzymatic hydrolysis	[187]

Search strategy: EN_AB:(high NEAR solids AND enzymatic NEAR hydrolysis) OR EN_AB:(high NEAR solids AND saccharification) OR EN_AB:(high NEAR gravity AND enzymatic NEAR hydrolysis) OR EN_AB:(high NEAR gravity AND saccharification) OR EN_AB:(high NEAR consistency AND enzymatic NEAR hydrolysis) OR EN_AB:(high NEAR consistency AND saccharification) EN_TI:(high NEAR solid* AND enzymatic NEAR hydrolysis) OR EN_TI:(high NEAR solids AND hydrolysis) OR EN_TI:(high NEAR dry AND enzymatic NEAR hydrolysis) OR EN_TI:(high NEAR solid* AND saccharification) OR EN_TI:(high NEAR gravity AND enzymatic NEAR hydrolysis) OR EN_TI:(high NEAR gravity AND saccharification) OR EN_TI:(high NEAR consistency AND enzymatic NEAR hydrolysis) OR EN_TI:(high NEAR consistency AND saccharification) OR EN_TI:(high NEAR consistency AND hydrolysis NEAR cellulose) NOT EN_TI:(oxidized OR dietary OR treatment OR high-protein OR extraction OR lignin OR battery OR maltodextrin OR raw OR alkalinuria OR potato OR polyvinyl)
^aDate of publication of US Patent Office, except for the document, “Method for the hydrolysis of lignocellulosic biomass.”
^bDate of publication of WO patent office

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ISSN: 2731-3654

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