From: Bioproduction of succinic acid from xylose by engineered Yarrowia lipolytica without pH control
Organism | Fermentation mode | Feedstock (xylose fraction) | Other sugars | Xylose consumed (g/L) | Succinic acid | Main by-products (g/L) | Reference | ||
---|---|---|---|---|---|---|---|---|---|
Titer (g/L) | Yielda (g/g) | Productivity (g/L/h) | |||||||
A. succinogenes 130Z | Batch | SSL (72.6%) | Galactose (12.2%), glucose (10.9%), mannose (4.2%), arabinose (0.1%) | 30.2 | 27.4 | 0.70 | 0.45 | FA (8.8) AA (12.6) | [45] |
B. succiniciproducens JF4016 | Batch | SSL (72.6%) | Galactose (12.2%), glucose (10.9%), mannose (4.2%), arabinose (0.1%) | 25.0 | 26.0 | 0.76 | 0.55 | FA (3.3) AA (8.3) | [45] |
A. succinogenes 130Z | Batch | Pure xylose | – | 22.00 | 14.2 | 0.64 | 0.67 | – | [46] |
A. succinogenes 130Z | Batch | SCB (-) | – | 52.00 | 22.5 | 0.43 | 1.01 | – | [46] |
E. coli recombinant SD121 | Batch | Pretreated mother liquor (51.7%) | Arabinose (10–15%), glucose (8–10%), galactose (8–10%) | 37.01 | 52.1 | 0.63 | 0.62 | AA (10) | [47] |
A. succinogenes CICC 11014 | Batch | Corncob hydrolysate (77.3%) | Glucose (2.8%), arabinose (12.9%), cellobiose (7.0%) | 38.1 | 23.64 | 0.58 | 0.49 | – | [48] |
E. coli BA204 | Batch dual phase | Pretreated cornstalk (80.7%) | Glucose (13.5%) | 8.1 | 11.13 | 1.03 | 0.70 | AA (2.5) | [49] |
E. coli BA408 | Batch | Corn stalk hydrolysate (81.6%) | Glucose (9.5%), arabinose (3.5%) | 23 | 23.1 | 0.85 | 0.24 | AA (< 0.5) | [50] |
B. succiniciproducens JF4016 | Batch | Pure xylose | – | 7.67 | 4.6 | 0.60 | 0.80 | FA (1.9), AA (2.6) | [51] |
A. succinogenes 130Z | Batch | Corn stover (73.4%) | Glucose (10.1%), galactose (4.9%), arabinose (11.6%) | 55.4 | 42.8 | 0.74 | 1.27 | FA (-), AA (-) | [33] |
Y. lipolytica PSA02004PP | Batch | Pure xylose | – | 60 | 11.2 | 0.19 | 0.13 | AA (8.5) | This study |
Y. lipolytica PSA02004PP | Batch | SCB (90.5%) | Glucose (6.0%), arabinose (3.6%) | 37.8 | 5.6 | 0.13 | 0.09 | AA (8.3) | This study |
Y. lipolytica PSA02004PP | Fed-batch | Pure xylose | – | 150 | 22.3 | 0.15 | 0.14 | AA (25) | This study |