Insights into the cellulose degradation mechanism of the thermophilic fungus Chaetomium thermophilum based on integrated functional omics

Table 1 Biomass-degrading enzymes in the genome of C. thermophilum

Type	Substrate	Enzyme activity	CAZy family	Number
Oxidases	Lignocellulose	Lytic polysaccharide monooxygenase	AA9	18
		Cellobiose dehydrogenase	AA3+AA8	2
		GMC oxidoreductase	AA3	8
		Oligosaccharide oxidase	AA7	13
		Copper radical oxidases	AA5	8
		Iron reductase	AA8	5
		Multicopper oxidase	AA1	5
		Class II lignin-modifying peroxidases	AA2	2
		Vanillyl-alcohol oxidase	AA4	2
		1,4-Benzoquinone reductase	AA6	1
Non-oxidases	Cellulose	Cellobiohydrolase	GH7	3
			GH6	2
		β-1,4-Glucosidase	GH3	7
			GH1	1
		β-1,4-Endoglucanase	GH5	5
			GH45	2
			GH6	1
			GH7	1
			GH12	1
	Xylan	β-1,4-Endoxylanase	GH10	4
			GH11	4
		β-1,4-Xylosidase	GH43	3
		Acetylxylan esterase	CE3	4
			CE1	2
			CE5	2
		α-Glucuronidase	GH67	1
			GH115	1
		Feruloyl esterase	CE1	2
		α-Arabinofuranosidase	GH43	3
			GH62	2
	(Galacto)mannan	β-1,4-Endomannase	GH5	1
			GH26	1
		β-1,4-Mannosidase	GH2	1
	Xyloglucan	β-1,4-Endoglucanase	GH74	1
	Pectin	Pectate lyase	PL3	2
			PL1	1
			PL2	1
		Exopolygalacturonase	GH28	1
		β-1,4-Galactosidase	GH2	1
			GH35	1
		Pectin methylesterase	CE8	1
		Carbohydrate esterase	CE15	2
			CE16	2
		Rhamnogalacturonan acetylesterase	CE12	1
	β-1,3;1,4-glucan	1,3-β-Endoglucanase	GH16	11
			GH17	3
			GH81	1
			GH55	1
			GH128	2
			GH131	2
		1,3-β-Exodoglucanase	GH55	3
			GH132	1
	Chitin	Exo-β-1,4-d-glucosaminidase	GH2	1
		Chitinase	GH18	9
			GH75	1
		β-Hexosaminidase	GH20	1
		Chitin-binding protein	CBM18	2
		Deacetylase	CE4	4
	Starch	α-Amylase	GH13	4
		α-Glucosidase	GH31	4
			GH15	3

ISSN: 2731-3654