Fig. 4

Diagrammatic representation of significantly differentially expressed genes associated with the fatty acid biosynthesis pathways, glycolysis, pentose phosphate pathway and TCA cycle when Schizochytrium was cultured under low-temperature conditions. Genes that were differentially regulated (|fold change|> = 2 and adjusted p value < 0.001) when Schizochytrium was cultured at 16 °C are indicated in red (upregulated) and blue (downregulated). HK glycolysis hexokinase, PFKA 6-phosphofructokinase, PGAM phosphoglycerate mutase, PC pyruvate carboxylase, PGD glucose-6-phosphate 1-dehydrogenase, PfaA polyketide synthase subunit A, PfaB polyketide synthase subunit B, PfaC polyketide synthase subunit C, ME malic enzyme, FAS fatty acid synthase, ELO long-chain fatty acid elongase, VLCR very long-chain 3-oxoacyl-CoA reductase, ACADM acyl-CoA dehydrogenase, ECHS enoyl-CoA hydratase, LSC succinyl-CoA synthetase