Fig. 5

Diagrammatic representation of significantly differentially expressed genes associated with the branched-chain amino acid pathway. Genes that were differentially regulated (fold change >  = 2 and adjusted p value <  = 0.001) when Schizochytrium was cultured at 16 °C are indicated in red (upregulated) and blue (downregulated). TAT tyrosine aminotransferase, HGD homogentisate 1,2-dioxygenase, FAH fumarylacetoacetase, OXCT 3-oxoacid CoA-transferase, ACCAT acetyl-CoA C-acetyltransferase, BCATC ketol-acid reductoisomerase, BCAT branched-chain amino acid aminotransferase, BCKDH 2-oxoisovalerate dehydrogenase E1 component, DBT 2-oxoisovalerate dehydrogenase E2 component, ACAMD acyl-CoA dehydrogenase, ECHS enoyl-CoA hydratase, GCDH glutaryl-CoA dehydrogenase, LEU 3-isopropylmalate dehydratase, IVD isovaleryl-CoA dehydrogenase, MCCB 3-methylcrotonyl-CoA carboxylase beta subunit, HMGCS hydroxymethylglutaryl-CoA synthase