Fig. 7
In silico flux analysis of acetyl-CoA source for lipid synthesis. The citrate transport from mitochondria to cytosol and ATP-citrate lyase which catalyzes the reaction ATP + citrate + Coenzyme-A acetyl-CoA + oxaloacetate + Pi + ADP in cytosol follow the red Y-scale; acyl-coA production (an artificial reaction represents acyl-coA Pool in the model); and lipid synthesis (an exchange reaction of lipid) follow the blue Y-scale. Bars indicate the standard errors of means of fluxes through each reaction. The C/N (g/g) refers to the ratio between the uptake rates of carbon and nitrogen sources