Fig. 3
From: Cell-based and cell-free biocatalysis for the production of d-glucaric acid
Schematic overview of heterologous GA synthesis pathways in engineered yeast [50, 55, 58]. Red text indicates key substances in the synthesis pathway of GA. Black and bold text represent heterologous enzymes involved in the production of GA. Myo-inositol (MI) or glucose can be used as the substrate for GA synthesis in vivo. GLK1 glucokinase-1, HXK hexokinase, Ino1 myo-inositol-1-phosphate synthase, Inm1 inositol monophosphatase 1, MIOX myo-inositol oxygenase, PPP pentose phosphate pathway, Udh uronate dehydrogenase