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Table 2 Statistical analysis of the FCCD for 2,3-BD production by B. subtilis CS13

From: Process optimization for mass production of 2,3-butanediol by Bacillus subtilis CS13

Factors

Mean square

Coefficient estimate

Standard error

F value

P value

Model

572.55

121.46

0.86

92.13

 < 0.0001

X1: Sucrose

1288.45

− 11.35

0.79

207.34

 < 0.0001

X2: Ammonium citrate

311.36

5.58

0.79

50.10

 < 0.0001

X3: MgSO4·7H2O

209.58

4.58

0.79

33.73

0.0002

X1X2

39.74

2.23

0.88

6.39

0.0299

X1X3

4.10

0.72

0.88

0.66

0.4353

X2X3

14.55

− 1.35

0.88

2.34

0.1569

X12

559.24

− 14.26

1.50

89.99

 < 0.0001

X22

264.94

− 9.82

1.50

42.63

 < 0.0001

X32

83.35

− 5.51

1.50

13.41

0.0044

Lack of Fit

7.40

  

1.47

0.3410

R2 = 0.9881

R2 (adj) = 0.9774

 

R2 (Pred) = 0.9054

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