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Table 3 Production of 2,3-BD by various microorganisms

From: Process optimization for mass production of 2,3-butanediol by Bacillus subtilis CS13

Strain

Substrate

Operation mode

2,3-BD titer (g/L)

2,3-BD productivity (g/L/h)

2,3-BD yield (g 2,3-BD/g substrate)

References

B. subtilis 168 (BSF9)

Glucose

Fed-batch

103.7

0.459

0.487

[9]

B. subtilis TUL322

Glucose

Fed-batch

75.73

0.66

0.31

[42]

B. amyloliquefaciens PBG

Glucose

Fed-batch

132.9

2.95

0.43

[6]

B. licheniformis DSM 8785

Glucose

Fed-batch

144.7

1.14

0.42

[30]

B. vallismortis B-14891

Glucose

Batch

60.4

1.10

0.33

[44]

S. cerevisiae CEN.PK2-1C

Glucose

Fed-batch

72.9

1.43

0.41

[45]

S. cerevisiae YHI030

Glucose

Fed-batch

81

0.26

0.41

[46]

K. oxytoca ME-UD-3

Glucose

Fed-batch

130

1.63

0.48

[47]

K. oxytoca GSC 12206

Glucose

Fed-batch

115

2.27

0.41

[31]

K. pneumoniae KG1

Glucose

Fed-batch

116

2.23

0.49

[5]

K. pneumoniae SDM

Glucose

Fed-batch

150

4.21

0.43

[29]

E. aerogenes KCTC 2190

Glucose

Fed-batch

118

2.18

0.42

[32]

P. polymyxa CJX518

Glucose

Fed-batch

71.7

1.33

0.39

[25]

B. subtilis CS13

Sucrose

Fed-batch

132.4

2.45

0.45

This work