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Fig. 8 | Biotechnology for Biofuels

Fig. 8

From: Interfacial molecular interactions of cellobiohydrolase Cel7A and its variants on cellulose

Fig. 8

(illustration adapted from [13])

Schematic of Cel7A–cellulose interfacial interactions leading to non-productive and productive binding. Sites at which Cel7A fully loads its active site with a cellodextrin chain are complexation sites while sites at which Cel7A binds without engaging its active site (e.g., only by its CBM) are adsorption sites. Productive binding occurs at complexation sites where complexed enzymes hydrolyze cellulose; non-productive binding occur at adsorption sites and at complexation sites where complexed enzymes cannot carry out hydrolysis

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