Fig. 7

Expression of genes in central metabolic pathway in wild-type (WT) and engineered M. thermophila strain JY518. Numbers represent RPKM ratio of JY518 strain to WT strain. Upregulated genes (ratio > 2, P value < 0.05) are shown in red; downregulated genes (ratio < 0.5, P value < 0.05) are shown in green. -, RPKM < 20 both in WT and JY518 strain at 3 day and 5 day of culture. Detailed data are shown in Additional file 1: Table S8