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Fig. 2 | Biotechnology for Biofuels

Fig. 2

From: Large-scale kinetic metabolic models of Pseudomonas putida KT2440 for consistent design of metabolic engineering strategies

Fig. 2

The directionality of transketolase 2 (TKT2) impacts the in silico essentiality of two genes encoding EDD and EDA from the Entner–Doudoroff pathway. a If TKT2 operates towards production of g3p, then due to the stoichiometric coupling transketolase 1 (TKT1) and transaldolase (TALA) are unidirectional and EDD and EDA are not in silico essential. b If TKT2 operates towards consumption of g3p, EDD and EDA are in silico essential irrespectively of the directionalities of TKT1 and TALA

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