Fig. 3

Distribution of the control coefficients of glucose uptake (GLCtex) and specific growth rate (growth) for the wild-type physiology of P. putida. The control coefficients of glucose uptake (a) and specific growth rate (b) were first computed using an unbiased sampling in ORACLE, and then further refined using the machine learning methodology iSCHRUNK (c, d). The green bars represent the mean values of the control coefficients, whereas the error bars correspond to the 25 and 75 percentiles of the distributions