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Table 2 Comparison of malic acid production with A. oryzae and different substrate concentrations after 192 h

From: Acetate as substrate for l-malic acid production with Aspergillus oryzae DSM 1863

Substrate c (substrate) (g/L) Consumed substrate (g/L) c (malic acid) (g/L) YP/S (g/g) YP/S, carbon (g/g) Overall Productivity (g/(L*h)) Maximum productivity (g/(L*h)) Time of maximum productivity (h)
HAc 10 9.72 ± 0.15 0.00 ± 0.00 0.00 0.00 0.000 0.000 0.00
  20 18.43 ± 1.54 1.42 ± 0.34 0.08 0.07 0.007 0.020 107.15
  30 29.64 ± 0.06 4.56 ± 0.23 0.15 0.14 0.024 0.076 92.25
  40 38.01 ± 1.74 7.04 ± 0.33 0.19 0.17 0.037 0.123 89.61
  45 44.14 ± 0.53 8.44 ± 0.42 0.19 0.17 0.044 0.122 85.05
  50 42.58 ± 0.80 8.45 ± 0.49 0.20 0.18 0.044 0.115 90.33
  55 37.55 ± 2.27 7.92 ± 0.29 0.21 0.19 0.041 0.081 95.38
Mixed HAc: 45 glucose: 5 HAc: 44.87 ± 0.30
glucose: 5.06 ± 0.04
9.95 ± 0.25 0.20 0.18 0.052 0.114 61.98
  HAc: 45 glucose: 10 HAc: 44.46 ± 0.30
glucose: 10.07 ± 0.03
12.15 ± 0.21 0.22 0.20 0.063 0.119 58.62
  HAc: 45 glucose: 15 HAc: 44.66 ± 0.33
glucose: 15.06 ± 0.04
14.18 ± 0.09 0.24 0.21 0.074 0.138 61.02
Glucosea 109 58.90 ± 0.86 38.75 ± 0.29 0.66 0.59 0.231 0.292 87.61
  1. a The values for 109 g/L glucose were determined for a cultivation time of 168 h
  2. HAc  acetic acid, YP/S (g/g)  substrate specific malic acid yield calculated as g(malic acid)/g(total consumed substrate(s)), YP/S, carbon (g/g)  substrate specific malic acid yield calculated as g(produced C from malic acid)/g(total consumed C from substrate(s))