TY - JOUR AU - Chen, Yumeng AU - Fan, Xingjia AU - Zhao, Xinqing AU - Shen, Yaling AU - Xu, Xiangyang AU - Wei, Liujing AU - Wang, Wei AU - Wei, Dongzhi PY - 2021 DA - 2021/03/08 TI - cAMP activates calcium signalling via phospholipase C to regulate cellulase production in the filamentous fungus Trichoderma reesei JO - Biotechnology for Biofuels SP - 62 VL - 14 IS - 1 AB - The filamentous fungus Trichoderma reesei is one of the best producers of cellulase and has been widely studied for the production of cellulosic ethanol and bio-based products. We previously reported that Mn2+ and N,N-dimethylformamide (DMF) can stimulate cellulase overexpression via Ca2+ bursts and calcium signalling in T. reesei under cellulase-inducing conditions. To further understand the regulatory networks involved in cellulase overexpression in T. reesei, we characterised the Mn2+/DMF-induced calcium signalling pathway involved in the stimulation of cellulase overexpression. SN - 1754-6834 UR - https://doi.org/10.1186/s13068-021-01914-0 DO - 10.1186/s13068-021-01914-0 ID - Chen2021 ER -