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Table 2 DHA yield in Schizochytrium sp. from the literatures and this study

From: Overproduction of docosahexaenoic acid in Schizochytrium sp. through genetic engineering of oxidative stress defense pathways

Schizochytrium sp. Strategy Cultivation mode Yield (g/L) Content (%TFA) Reference
S056
HX-308
Optimization of sea salt
ALE
Shake flask
1,500-L fermentor
8.0
38.1
44.4
53.3
[30]
[31]
HX-308 Addition of ascorbic acid 5-L bioreactor 38.3 54.5 [3]
SR21 Addition of inositol Shake flask 8.5 37.3 [33]
HX-308
MYA1381
ATCC20888
ATCC20888
ATCC20888
Continuous feeding
Metabolic engineering
Metabolic engineering
Metabolic engineering
Metabolic engineering
Fed-batch
Shake-flask/ Fed-batch
Shake-flask
Shake-flask
Shake-flask/ Fed-batch
38.4
7.0/ 47.4
3.5
6.4
8.8/ 13.3
55.0
42.9
N.C
37.9
42.8
[32]
[11]
[12]
[10]
This study
  1. ALE: Adaptive laboratory evolution, N.C.: not calculated