Fig. 7
Carotenoid biosynthetic pathways in C. zofingiensis. AACT, acetoacetyl-CoA thiolase; AAT, long-chain-alcohol O-fatty-acyltransferase; BKT, beta-carotenoid ketolase; CDP-ME, 4-diphosphocytidyl-2-C-methylerythritol; CDP-MEP, 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; CHYb, beta-carotenoid hydroxylase; CMK, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; CMS, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; CRTISO, carotenoid isomerase; CYP97A, cytochrome P450 beta hydroxylase; CYP97C, cytochrome P450 epsilon hydroxylase; DMAPP, dimethylallyl pyrophosphate; DXR, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; DXP, 1-deoxy-D-xylulose 5-phosphate; DXS, 1-deoxy-D-xylulose 5-phosphate synthase; FPP,farnesyl diphosphate; FPPS, farnesyl diphosphate synthase; GAP, glyceraldehyde 3-phosphate; GGPP, geranylgeranyl diphosphate; GGPPS, geranylgeranyl diphosphate synthase; GPP, geranyl diphosphate; GPPS, geranyl diphosphate synthase; HCS, hydroxymethylglutaryl-CoA synthase; HDR, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase; HDS, 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; HGM-CoA, 3-hydroxy-3-methylglutaryl-CoA; HMB-PP, (E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate; IPP, isopentenyl pyrophosphate; IPPI, isopentenyl-diphosphate Delta-isomerase; LCYb, lycopene beta cyclase; LCYe, lycopene epsilon cyclase; LD, lipid droplet; MCS, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; MEcPP, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; MEP, 2-C-methylerythritol 4-phosphate; NXS, neoxanthin synthase; PDS, phytoene desaturase; PSY, phytoene synthase; VDE, violaxanthin de-epoxidase; ZDS, zeta-carotene desaturase; ZEP, zeaxanthin epoxidase; ZISO, zeta-carotene isomerase