The oleaginous astaxanthin-producing alga Chromochloris zofingiensis: potential from production to an emerging model for studying lipid metabolism and carotenogenesis

Zhang, Yu; Ye, Ying; Bai, Fan; Liu, Jin

doi:10.1186/s13068-021-01969-z

Biotechnology for Biofuels and Bioproducts

Table 2 Putative genes involved in fatty acid biosynthesis, desaturation and degradation in C. zofingiensis

From: The oleaginous astaxanthin-producing alga Chromochloris zofingiensis: potential from production to an emerging model for studying lipid metabolism and carotenogenesis

Gene name abbreviations	Gene ID		Gene description	References
Gene name abbreviations	JGI v5.2.3.2	GenBank	Gene description	References
Acetyl-CoA production
PDHC E1A	Cz03g08090		Pyruvate dehydrogenase complex, E1 α-subunit
PDHC E1B	Cz01g37230		Pyruvate dehydrogenase complex, E1 β-subunit
ACS1	Cz09g15060	MK886788	Acetyl-CoA synthetase	[202]
ACS2	Cz12g10100	MK886789	Acetyl-CoA synthetase	[202]
De novo fatty acid synthesis
α-CT	Cz02g12030		Carboxyltransferase α-subunit (ACCase complex)
β-CT	Cz02g17060		Carboxyltransferase β-subunit (ACCase complex)
BCCP	Cz03g28270		Biotin carboxyl carrier protein (ACCase complex)
BC	Cz13g10110	GQ996717	Biotin carboxylase (ACCase complex)	[156]
MCT	Cz13g05150		Malonyl-CoA:acyl carrier protein transacylase
KASI	Cz02g14160		3-ketoacyl-ACP synthase, I
KASII	UNPLg00257		3-ketoacyl-ACP synthase, II
KASIII	Cz18g03070		3-ketoacyl-ACP synthase, III
KAR	Cz01g34370		3-ketoacyl-ACP reductase
HAD	Cz01g09160		3-ketoacyl-ACP dehydratase
ENR	Cz11g20040		Enoyl-ACP reductase
Fatty acid activation and export
FAT	Cz04g05080		Acyl-ACP thioesterase
FAX1	Cz01g44210		Fatty acid export
FAX2	Cz08g09020		Fatty acid export
FAX3	Cz02g41140		Fatty acid export
LACS1	Cz12g27140	MN317384	Long-chain acyl-CoA synthetase	[151]
LACS2	Cz11g20120	MN317385	Long-chain acyl-CoA synthetase; ER^a	[151]
LACS3	Cz01g36150	MN317386	Long-chain acyl-CoA synthetase; ER^a, LD^a	[151]
LACS4	Cz07g22230	MN317387	Long-chain acyl-CoA synthetase; ER^a, LD^a	[151]
LACS6	Cz08g09130	MN317389	Long-chain acyl-CoA synthetase	[151]
Fatty acid desaturation
SAD1	Cz04g09090	GQ996719	Stearoyl-ACP desaturase	[156]
SAD2	Cz13g17200		Stearoyl-ACP desaturase
FAD6A	Cz08g04110		ω-6 fatty acid desaturase, chloroplastic type
FAD6B	Cz11g21120		ω-6 fatty acid desaturase like, chloroplastic type
FAD2	Cz03g33220		ω-6 fatty acid desaturase, ER type
FAD7A	Cz04g31180		ω-3 fatty acid desaturase
FAD7B	Cz06g28130		ω-3 fatty acid desaturase
FAD5A	Cz07g00120		MGDG-specific palmitate ∆7 desaturase
FAD5B	Cz06g00170		MGDG-specific palmitate ∆7 desaturase
FAD5C	Cz13g01140		MGDG-specific palmitate ∆7 desaturase like
FAD3A	Cz06g12050		∆4/∆6 desaturase like
FAD3B	UNPLg00012		∆4/∆6 desaturase like
FAD4	Cz12g10230		∆3 palmitate desaturase
Fatty acid β-oxidation
LACS5	Cz05g30060	MN317388	Long-chain acyl-CoA synthetase, peroxisome^a	[151]
AOX1	Cz16g14110		Acyl-CoA oxidase
AOX2	Cz07g30210		Acyl-CoA oxidase
AOX3	Cz07g18040		Acyl-CoA oxidase
AOX4	Cz08g04130		Acyl-CoA oxidase
AOX5	Cz17g14150		Acyl-CoA oxidase
ECH1	Cz16g07140		enoyl-CoA hydratase
ECH2	Cz03g36260		enoyl-CoA hydratase
ECH3	Cz04g19010		Enoyl-CoA hydratase/isomerase
ECH4	Cz06g10230		Enoyl-CoA hydratase
ECH5	Cz09g10030		Enoyl-CoA hydratase
HCD	Cz11g22170		3-hydroxyacyl-CoA dehydrogenase
KATO	Cz06g36270		3-ketoacyl-CoA thiolase

^aWhere experimental evidence of a subcellular localization is available

Back to article page

ISSN: 2731-3654

Contact us

General enquiries: journalsubmissions@springernature.com