Fig. 1From: Engineering of Yarrowia lipolytica transporters for high-efficient production of biobased succinic acid from glucoseSchematic diagram of the SA biosynthetic pathways and its export route in Y. lipolytica. There are three major metabolic pathways involve in the SA biosynthesis of Y. lipolytica: (1) reductive branch of the TCA cycle (red line); (2) oxidative TCA cycle (green line); (3) glyoxylate bypass (blue line). Dotted lines indicated the deleted genes for SA accumulation. Pck phosphoenolpyruvate carboxykinase, Scs2 succinyl-CoA synthase β subunit, Frd fumarate reductase, Mls malate synthase, Icl isocitrate lyase, Yhm2 mitochondrial citrate transporterBack to article page