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Fig. 1 | Biotechnology for Biofuels

Fig. 1

From: Engineering of Yarrowia lipolytica transporters for high-efficient production of biobased succinic acid from glucose

Fig. 1

Schematic diagram of the SA biosynthetic pathways and its export route in Y. lipolytica. There are three major metabolic pathways involve in the SA biosynthesis of Y. lipolytica: (1) reductive branch of the TCA cycle (red line); (2) oxidative TCA cycle (green line); (3) glyoxylate bypass (blue line). Dotted lines indicated the deleted genes for SA accumulation. Pck phosphoenolpyruvate carboxykinase, Scs2 succinyl-CoA synthase β subunit, Frd fumarate reductase, Mls malate synthase, Icl isocitrate lyase, Yhm2 mitochondrial citrate transporter

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