Fig. 1From: Crystal structure and functional characterization of an oligosaccharide dehydrogenase from Pycnoporus cinnabarinus provides insights into fungal breakdown of lignocelluloseCatalytic cycle of GDHs. The enzyme in the oxidized resting state accepts electrons from a reducing sugar, like D-glucose, which is oxidized at the C1 position and converted into D-glucono-δ-lactone; this causes the protein solution to turn from yellow to colorless, due to the reduction of the FAD cofactor. In the second half-reaction electrons are transferred from reduced FADH2 to aromatic electron acceptors, such as quinones. The enzymatic product D-glucono-δ-lactone undergoes spontaneous hydrolysis in waterBack to article page