Establishment of a resource recycling strategy by optimizing isobutanol production in engineered cyanobacteria using high salinity stress

Table 2 Comparison of metabolic engineered cyanobacteria for biobutanol production

Product	Host	Engineering genes	Specific modification	Titer productivity	References
Isobutanol	S. elongatus	alsS ilvC ilvD in NSII kivD yqhD in NSI	Initial OD₇₃₀ at 1.0 Enhancing rubisco	450 mg/L 150 mg/L/OD	[11]
Isobutanol	Synechocystis	kivD adhA	Mixotrophic condition In situ removal of isobutanol	298 mg/L 24.8 mg/L/OD	[23]
Isobutanol	S. elongatus	alsS ilvC ilvD in NSII kivD yqhD in NSI	Deleting a glgC gene	550 mg/L 122 mg/L/OD	[22]
Isobutanol	Synechocystis	alsS ilvC ilvD kivD slr1192	HCl-titrated culture	911 mg/L 227 mg/L/OD	[24]
Isobutanol	Synechocystis	kivD slr1192	Addition of isobutyraldehyde	290 mg/L 72.5 mg/L/OD	[33]
Isobutanol	S. elongatus	alsS ilvC ilvD kivD adhA in NSI	High salinity stress	637 mg/L 290 mg/L/OD	This study
n-Butanol	S. elongatus	ter in NSI atoB adhE2 crt hbd in NSII	Anoxic condition	14.5 mg/L 5.8 mg/L/OD	[7]
n-Butanol	S. elongatus	ter in NSI nphT7 bldh yqhD phaJ phaB in NSII	Engineering ATP consumption	30 mg/L 6.0 mg/L/OD	[8]
n-Butanol	Synechocystis	ter phaJ pduP nphT7 fadB slr1192	Modular pathway engineering	836 mg/L 199 mg/L/OD	[10]
n-Butanol	S. elongatus	ter in NSI nphT7 pduP yqhD phaJ phaB in NSII	Using oxygen-tolerant PduP	404 mg/L 66.7 mg/L/OD	[9]

ISSN: 2731-3654