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Fig. 4 | Biotechnology for Biofuels

Fig. 4

From: Tryptophan plays an important role in yeast’s tolerance to isobutanol

Fig. 4

Transcriptomic analysis of the tryptophan pathway under isobutanol stress. The wild type and tryptophan-defective strains were studied under four different conditions: with/without isobutanol and/or supplemental tryptophan. Total RNAs were harvested after 24 h for RNA sequencing. a Principal component analysis (PCA) using the RPKM data. Each spot represents 6933 genes’ expression levels. In terms of the distance between spots, the wild type and the mutant strain were not very different under no isobutanol stress, but had large differences under isobutanol stress. Adding external tryptophan mitigated the effect of isobutanol stress on the mutant strain. b Heatmap and hierarchical clustering showed similar result as the PCA plot

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