Fig. 4

Effects of the expression level of the cadA gene on cell growth and lysine/cadaverine biosynthesis in Methylomonas sp. DH-1. A Genetic structure of cadA under the control of five promoters. Cadaverine production (B), growth (C), and lysine synthesis (D) of wild-type and five engineered Methylomonas sp. DH-1 strains in an NMS medium with a supplementation of 30% methane (v/v) as the sole carbon source. Data indicate mean ± SEM (n = 3)