Fig. 3

Proposed response of central carbon metabolism in HC-cultivated P. tricornutum based on proteomic data. The upregulated enzymes are indicated by red color, and the unchanged enzymes are indicated by black color, while the non-detected enzymes are indicated by grey color. Details about these differently expressed proteins under HC conditions are shown in additional excel sheets (Additional file 1: Table S1). RuBP: ribulose-1,5-biphosphate; 3-PGA: 3-phosphoglycerate; BPG: 1,3-biphosphoglyceride; GAP: glyceraldehyde-3-phosphate; DHAP: dihydroxyacetone phosphate; FBP: fructose-1,6- biphosphate; F6P: fructose-6-phosphate; G6P: glucose-6-phosphate; 6PG: 6-phosphogluconate; Ru5P: ribulose-5-phosphate; R5P: ribose-5-phosphate; Xu5p: xylulose-5-phosphate; S7P: sedoheptulose-7-phosphate; SBP: sedoheptulose-1, 7-biphosphate; E4P: erythrose-4-phosphate; 2-PGA: 2-phosphoglycerate; PEP: phosphoenolpyruvate; PYR: pyruvate; OAA: oxaloacetate; MAL: malate; CIT: citrate; ICA: isocitrate; α-KG: α-ketoglutarate; SUC: succinate; G1P: glucose-1-phosphate; LHC: light harvesting chlorophyll; PS: photo system. G6PDH: glucose-6-phosphate dehydrogenase; 6PGDH: 6-phosphogluconate dehydrogenase; GPI; glucose-6-phosphate isomerase; FBA: fructose-1,6-diphosphate aldolase; RuBisco: ribulose bisphosphate carboxylase; PRK: phosphoribulokinase; PGK: phosphoglycerate kinase; TIM: triose phosphate isomerase; GAPDH: glyceraldehyde 3-phosphate dehydrogenase; TAL: transaldolase; TKL: transketolase; PGAM: phosphoglycerate mutase; PK: pyruvate kinase; PDH: pyruvate dehydrogenase; CS: citrate synthase; ICDH: isocitrate dehydrogenase; α-KGDH: α-ketoglutarate dehydrogenase; SDH: succinate dehydrogenase; SCS: succinate-CoA ligase; MDH: malate dehydrogenase; ACC: acetyl-CoA carboxylase; UGP/PGM: UDP-glucose-pyrophosphorylase/phosphoglucomutase